Vitamin D Receptor Gene Polymorphisms Associated with Childhood Autism
نویسندگان
چکیده
منابع مشابه
Vitamin D Receptor Gene Polymorphisms Associated with Childhood Autism
BACKGROUND Autism spectrum disorder (ASD) is a group of heterogeneous, behaviorally defined disorders whereby currently no biological markers are common to all affected individuals. A deregulated immune response may be contributing to the etiology of ASD. The active metabolite of vitamin D₃ has an immunoregulatory role mediated by binding to the vitamin D receptor (VDR) in monocyte, macrophages...
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BACKGROUND Emerging data suggest a role for the vitamin D receptor (VDR) in lipogenesis and adipocyte differentiation. OBJECTIVE Our objective was to evaluate the association of VDR gene variants and adiposity phenotypes in an epidemiologic study. DESIGN In a sample of 1773 healthy female adults recruited from western New York, we tested for the association of 14 VDR single nucleotide polym...
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Objective(s) Deregulation of the immune system through allied factors and cytokine responses are thought to be important contributors to the pathogenesis of asthma. Vitamin D3 and its nuclear receptor appear to be factors that maybe involved in regulating immune responses during the progression of asthma. The aim of this study was to investigate the association between polymorphisms in intron ...
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Both genetic and environmental factors have been implicated in the etiology of autism spectrum disorder (ASD). This case-control study aimed to determine the association of single-nucleotide polymorphisms (SNPs) rs731276 (TaqI), rs1568820 (Cdx2), rs1544410 (BsmI), and rs2228570 (FokI) in the vitamin D receptor (VDR) gene with susceptibility of childhood ASD and severity of the disease. A total ...
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Objective: The role of vitamin D has soared to a pinnacle in recent years with functions affecting 229 human genes linked to cardiovascular, autoimmune, humoral, pulmonary and neurological diseases. Relationship between obesity and vitamin D has not as yet been fully established. The objective of the study was to determine the possible relationship between Vitamin D receptor (VDR) gene polymorp...
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ژورنال
عنوان ژورنال: Brain Sciences
سال: 2017
ISSN: 2076-3425
DOI: 10.3390/brainsci7090115